All I see is a gray box!
What's being shown?
How do I control which sequences are displayed?
What does the options menu do?
Bugs/Known Issues/To-do
Where is the source code?
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This program displays the exon structure of the alpha subunit of the large-conductance calcium-activated (BK) K+ channel. Each BK channel sequence in mouse, rat, cow, human, chicken, drosophila and C. Elegans unigene clusters were mapped with BLAST to the Mouse, Human, Chicken and Drosophila genomes. Each row in the main viewing area represents a distinct Genbank sequence. Each point in the main viewing area is a region of homology between the Genbank sequence and the genomic sequence. The red lines at the top of the main viewing area represent the known transmembrane domains of the BK channel.
In order to catalog alternative splices of the BK channel, we chose one transcript as our reference sequence. The 28 exons in the reference sequence were mapped to each genome. The vertical lines in the main viewing area reflect the boundaries of these 28 reference exons. We define an alternative splice as a transcript that has a different exon structure from the reference sequence.The right panel controls which sequences are displayed and gives information about selected exons and provides a link to Genbank. This screenshot shows the function of each section of the right panel: